Biochemistry and Drug Development

Biochemistry, sometimes known as natural hormones, is the study of chemical procedures in living creatures. Most of the hormones deal with the elements, functions and relationships of cell elements such as necessary protein, sugars, fats, nucleic chemicals and other bio-molecules. Among the multitude of different bio-molecules, many are complicated and large substances called bio-polymers, which are consisting of similar duplicating subunits called monomers.

Drug development is a cover phrase used to determine the procedure of providing a new drug to the industry once a cause substance has been determined through the procedure of drug growth. It contains pre-clinical research (microorganisms/animals) and numerous studies (on humans) and may consist of the step of acquiring regulating acceptance to promote the drug.

Following rapid public and financial growth, more and more people have obtained the entry to sufficient knowledge and the awareness of the importance of chemistry to individual health. Because of this trend, more and more individuals have the interest and perceptive ability to study and think about the pathological procedures and treatment of human illnesses, – particularly those high occurrence illnesses with great public financial effect, such as heart illnesses, most cancers, infectious illnesses, metabolic conditions etc.

Actually, many medication used in present clinical practice are focusing on either the metabolic routes or the signaling pathways that control the metabolic procedures. For example, aspirin has been used as a painkiller, a non-steroidal anti-inflammatory drug and an anticoagulant in avoidance of heart disorders; these pharmacological programs are dependent on its inhibitory effect on oxygenation action that is indispensable for the bio-synthesis of prostaglandins.

Moreover, new treatments in development, such as histone acetylene inhibitors, also are centered on solid biochemical fundamentals. Lastly, side results, level of resistance, bio-transformation and fingertips of medication in human system also involve complicated biochemical procedures.

Accordingly, all these biochemical processes, regulating systems of mobile metabolic rate, changes of metabolic procedures under pathological declares and the causes of these disease-related metabolic changes become significantly interesting topics not only for scientists, health experts and medication designers, but also for sufferers, upcoming experts and normal visitors.

In addition to small molecule-based medication, new techniques such as bioengineering and gene treatments, to condition control are growing. Although those new healing techniques are seemingly not directly related to chemistry, in fact, chemistry continues to be the base for the focus on recognition, focus on approval, bioengineering procedures, and the control of transgene concept in the case of gene treatments.

The completion of human genome project has not only accelerated the speed of biochemical discoveries and pharmaceutical development, but also has revealed the unexpected fact that many gene products have not been functionally or biochemically recognized, and that many aspects of basic cell metabolism, particularly under various disease states, remain unclear.

Consequently, the post-genomic era becomes a golden era for biochemical research, medication focus on recognition and pharmaceutical growth. This growing knowledge body to all your customers become a new challenge, the mixture of digital handling, internet technology and Open Access policy provides an ideal way in order to meet this task.

For more information, you can view list of chemical journals.

Steve Liem

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